WEKO3
インデックスリンク
アイテム
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可溶性型リソソーム膜糖タンパク質(lamp-2)のラット肝リソソームからの精製とその性質
https://fukuyama-u.repo.nii.ac.jp/records/7129
https://fukuyama-u.repo.nii.ac.jp/records/712943d52c45-2722-4dcb-93db-fc7effc41c24
名前 / ファイル | ライセンス | アクション |
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KJ00005784728.pdf (48.3 kB)
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
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公開日 | 1999-01-01 | |||||
タイトル | ||||||
タイトル | 可溶性型リソソーム膜糖タンパク質(lamp-2)のラット肝リソソームからの精製とその性質 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Purification and characterization of a soluble form of lysosome-associated membrane glycoprotein-2 (lamp-2) from rat liver lysosomal contents | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ページ属性 | ||||||
内容記述タイプ | Other | |||||
内容記述 | P(論文) | |||||
記事種別(日) | ||||||
値 | 発表論文抄録 | |||||
著者名(日) |
赤崎, 健司
× 赤崎, 健司× 辻, 宏 |
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著者名よみ | ||||||
識別子Scheme | WEKO | |||||
識別子 | 37364 | |||||
姓名 | アカサキ, ケンジ | |||||
著者名よみ | ||||||
識別子Scheme | WEKO | |||||
識別子 | 37365 | |||||
姓名 | ツジ, ヒロシ | |||||
著者名(英) | ||||||
識別子Scheme | WEKO | |||||
識別子 | 37366 | |||||
姓名 | Akasaki, Kenji | |||||
言語 | en | |||||
著者名(英) | ||||||
識別子Scheme | WEKO | |||||
識別子 | 37367 | |||||
姓名 | Tsuji, Hiroshi | |||||
言語 | en | |||||
著者所属(日) | ||||||
値 | 福山大学薬学部 | |||||
著者所属(日) | ||||||
値 | 福山大学薬学部 | |||||
著者所属(英) | ||||||
言語 | en | |||||
値 | FACULTY OF PHARMACY & PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY | |||||
著者所属(英) | ||||||
言語 | en | |||||
値 | FACULTY OF PHARMACY & PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY | |||||
抄録(日) | ||||||
内容記述タイプ | Other | |||||
内容記述 | ラット肝リソソーム膜には1amp-2と呼ばれる多数の糖鎖を有する糖タンパク質が存在する。lamp-2はリソソーム膜画分だけでなく可溶性画分にも存在する。本論文では可溶性のlamp-2(SF-lamp-2)を精製して、その性質を明らかにした。SF-lamp-2は膜結合型lamp-2(MF-lmap-2)のC-末端側にある膜結合部分と細胞質に突き出た短いペプチドが欠落していることが明らかになった。 | |||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Lysosomal membrane of rat liver contains a highly glycosylated protein referred to as lamp-2. Lamp-2 occurs to a significant extent in a soluble fraction of rat liver lysosomes. The soluble form of lamp-2 (SF-lamp-2) was purified to electrophoretic homogeneity. An apparent molecular weight Mr of SF-lamp-2 on sodium dodecy sulfate-polyacrylamide gel electrophoresis was determined to be 91,000 which is 5,000 less than that of the membranous form of lamp-2 (MF-lamp-2). SF-and MF-lamp-2 were very similar to each other in terms of sialic acid content, NH_2-terminal amino acid sequence and isoelectric point. Gel filtration data indicated that native SF-lamp-2 has an M_r = 360,000. Taken together, SF-lamp-2 forms a tetrameric structure consisting of a homogenous polypeptide lacking a membrane-spanning domain and a cytoplasmic tail near the COOH-terminus. | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10064550 | |||||
書誌情報 |
福山大学薬学部研究年報 en : Annual report of the Faculty of Pharmacy & Pharmaceutical Sciences, Fukuyama University 巻 17, p. 85, 発行日 1999 |