{"created":"2023-06-19T09:51:36.402311+00:00","id":8819,"links":{},"metadata":{"_buckets":{"deposit":"8e763bf3-6148-451c-a4b1-3c7e0ac48751"},"_deposit":{"created_by":18,"id":"8819","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"8819"},"status":"published"},"_oai":{"id":"oai:fukuyama-u.repo.nii.ac.jp:00008819","sets":["502:503:627:779"]},"author_link":["46151","45674","46146","46147","46150","46145","45371","45337","46149","45108","45373","46148","46152","46153","46154","45106"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"30","bibliographicPageEnd":"15","bibliographicPageStart":"15","bibliographic_titles":[{"bibliographic_title":"福山大学薬学部研究年報"},{"bibliographic_title":"Annual report of the Faculty of Pharmacy & Pharmaceutical Sciences, Fukuyama University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A simple and highly sensitive high-performance liquid chromatography method for the determination of pipecolic acid in mouse brain areas was developed. After homogenization of brain and pretreatment with o-phthalaldehyde, the pipecolic acid and (2S,3S)-3-methylpyrrolidine-2-carboxylic acid (internal standard) were derivatized with 4-(5,6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsulfonyl chloride at 70 °C for 15 min in basic medium (pH 9.0). The fluorescent derivatives of pipecolic acid and internal standard were separated on a reversed-phase column by stepwise elution using acetic acid (30 mM)–acetonitrile at 50 °C and detected by fluorescence measurement at 316 nm (excitation) and 403 nm (emission). The detection limit (signal-to-noise ratio=3) of pipecolic acid was 13 fmol per injection. The recovery was about 106.7%. The precision (relative standard deviation) was 3.2%.","subitem_description_type":"Abstract"}]},"item_10002_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"A simple and highly sensitive high-performance liquid chromatography method for the determination of pipecolic acid in mouse brain areas was developed. After homogenization of brain and pretreatment with o-phthalaldehyde, the pipecolic acid and (2S,3S)-3-methylpyrrolidine-2-carboxylic acid (internal standard) were derivatized with 4-(5,6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsulfonyl chloride at 70 °C for 15 min in basic medium (pH 9.0). The fluorescent derivatives of pipecolic acid and internal standard were separated on a reversed-phase column by stepwise elution using acetic acid (30 mM)–acetonitrile at 50 °C and detected by fluorescence measurement at 316 nm (excitation) and 403 nm (emission). The detection limit (signal-to-noise ratio=3) of pipecolic acid was 13 fmol per injection. The recovery was about 106.7%. The precision (relative standard deviation) was 3.2%.","subitem_description_type":"Other"}]},"item_10002_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"46147","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Inoue, Hirofumi"}]},{"nameIdentifiers":[{"nameIdentifier":"46148","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sakata, Yasuhiko"}]},{"nameIdentifiers":[{"nameIdentifier":"46149","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nishio, Hiroaki"}]},{"nameIdentifiers":[{"nameIdentifier":"46150","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tokumo, Kohji"}]},{"nameIdentifiers":[{"nameIdentifier":"46151","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kojima, Eijiro"}]},{"nameIdentifiers":[{"nameIdentifier":"46152","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Date, Yuuko"}]},{"nameIdentifiers":[{"nameIdentifier":"46153","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tamura, Yutaka"}]},{"nameIdentifiers":[{"nameIdentifier":"46154","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tsuruta, Yasuto"}]}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"福山大学薬学部"}]},"item_10002_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1248/bpb.34.287","subitem_relation_type_select":"DOI"}}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10064550","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0288-724X","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"井上, 裕文"}],"nameIdentifiers":[{"nameIdentifier":"45108","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000006296797","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000006296797"}]},{"creatorNames":[{"creatorName":"阪田, 安彦"}],"nameIdentifiers":[{"nameIdentifier":"46145","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000270162760","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000270162760"}]},{"creatorNames":[{"creatorName":"西尾, 廣昭"}],"nameIdentifiers":[{"nameIdentifier":"45373","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000014625804","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000014625804"}]},{"creatorNames":[{"creatorName":"徳毛, 孝至"}],"nameIdentifiers":[{"nameIdentifier":"45371","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000014625915","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000014625915"}]},{"creatorNames":[{"creatorName":"小嶋, 英二朗"}],"nameIdentifiers":[{"nameIdentifier":"45674","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000345371922","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000345371922"}]},{"creatorNames":[{"creatorName":"伊達, 有子"}],"nameIdentifiers":[{"nameIdentifier":"45337","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000005189599","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000005189599"}]},{"creatorNames":[{"creatorName":"田村, 豊"}],"nameIdentifiers":[{"nameIdentifier":"46146","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000004460018","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000004460018"}]},{"creatorNames":[{"creatorName":"鶴田, 泰人"}],"nameIdentifiers":[{"nameIdentifier":"45106","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000005174471","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000005174471"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-25"}],"displaytype":"detail","filename":"30-15.pdf","filesize":[{"value":"95.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"井上裕文(発表論文抄録(2011))","url":"https://fukuyama-u.repo.nii.ac.jp/record/8819/files/30-15.pdf"},"version_id":"9f3312ed-23d8-4c14-9600-93aab9f43bb9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"pipecolic acid","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"brain","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fluorescent detection","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HPLC","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"4-(5,6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsulfonyl chloride","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"脳部位別組織中ピペコリン酸の簡便な高感度蛍光JPLC分析法(発表論文抄録(2011))","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"脳部位別組織中ピペコリン酸の簡便な高感度蛍光JPLC分析法(発表論文抄録(2011))"},{"subitem_title":"A Simple and Highly Sensitive HPLC Method with Fluorescent Detection for Determination of Pipecolic Acid in Mouse Brain Areas","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"18","path":["779"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-25"},"publish_date":"2017-12-25","publish_status":"0","recid":"8819","relation_version_is_last":true,"title":["脳部位別組織中ピペコリン酸の簡便な高感度蛍光JPLC分析法(発表論文抄録(2011))"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-06-19T10:16:12.536090+00:00"}