{"created":"2023-06-19T09:51:33.794780+00:00","id":8761,"links":{},"metadata":{"_buckets":{"deposit":"b7256785-90ce-4933-83f2-f9f2f3bcc731"},"_deposit":{"created_by":18,"id":"8761","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"8761"},"status":"published"},"_oai":{"id":"oai:fukuyama-u.repo.nii.ac.jp:00008761","sets":["502:503:627:783"]},"author_link":["45807","45810","45806","45805","45305","45809","45808","45081","45075"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"31","bibliographicPageEnd":"23","bibliographicPageStart":"23","bibliographic_titles":[{"bibliographic_title":"福山大学薬学部研究年報"},{"bibliographic_title":"Annual report of the Faculty of Pharmacy & Pharmaceutical Sciences, Fukuyama University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Total syntheses of (±)-carquinostatin A (1), and (R)-(−)-carquinostatin A (1a) together with its enantiomer, (S)-(+)-carquinostatin A (1b), possessing radical scavenging activity, were newly achieved. (±)-Carquinostatin A (1) was synthesized from 1-acetonyl-6-bromo-3-ethoxy-2-methylcarbazole (6), which was derived from the known 1-acetonyl-3-ethoxy-2-methylcarbazole (5). Introduction of a prenyl group at the 6-position of carbazole was successful in two steps. For the synthesis of (R)-(−)-carquinostatin A (1a) and (S)-(+)-carquinostatin A (1b), (R)-(−)-1-(2-acetoxypropyl)-3-hydroxy-2-methylcarbazole (15a) and (S)-(+)-3-hydroxy-1-(2-hydroxypropyl)-2-methylcarbazole (15b), prepared by lipase-QLM catalyzed enantioselective transesterification of 3-hydroxy-1-(2-hydroxypropyl)-2-methylcarbazole (14), were used as the chiral starting material.","subitem_description_type":"Abstract"}]},"item_10002_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Total syntheses of (±)-carquinostatin A (1), and (R)-(−)-carquinostatin A (1a) together with its enantiomer, (S)-(+)-carquinostatin A (1b), possessing radical scavenging activity, were newly achieved. (±)-Carquinostatin A (1) was synthesized from 1-acetonyl-6-bromo-3-ethoxy-2-methylcarbazole (6), which was derived from the known 1-acetonyl-3-ethoxy-2-methylcarbazole (5). Introduction of a prenyl group at the 6-position of carbazole was successful in two steps. For the synthesis of (R)-(−)-carquinostatin A (1a) and (S)-(+)-carquinostatin A (1b), (R)-(−)-1-(2-acetoxypropyl)-3-hydroxy-2-methylcarbazole (15a) and (S)-(+)-3-hydroxy-1-(2-hydroxypropyl)-2-methylcarbazole (15b), prepared by lipase-QLM catalyzed enantioselective transesterification of 3-hydroxy-1-(2-hydroxypropyl)-2-methylcarbazole (14), were used as the chiral starting material.","subitem_description_type":"Other"}]},"item_10002_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"45808","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000367427671","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000367427671"}],"names":[{"name":"稗田, 雄三"}]},{"nameIdentifiers":[{"nameIdentifier":"45075","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000005189344","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000005189344"}],"names":[{"name":"町支, 臣成"}]},{"nameIdentifiers":[{"nameIdentifier":"45809","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000337100339","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000337100339"}],"names":[{"name":"内田, 佳成"}]},{"nameIdentifiers":[{"nameIdentifier":"45305","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000005179805","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000005179805"}],"names":[{"name":"藤岡, 晴人"}]},{"nameIdentifiers":[{"nameIdentifier":"45810","nameIdentifierScheme":"WEKO"}],"names":[{"name":"藤井, さゆり"}]},{"nameIdentifiers":[{"nameIdentifier":"45081","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000014453717 ","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000014453717 "}],"names":[{"name":"日比野, 俐"}]}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"福山大学薬学部"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10064550","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0288-724X","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hieda, Yuhzo"}],"nameIdentifiers":[{"nameIdentifier":"45805","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Choshi, Tominari"}],"nameIdentifiers":[{"nameIdentifier":"45806","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Uchida, Yoshinari"}],"nameIdentifiers":[{"nameIdentifier":"45807","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-20"}],"displaytype":"detail","filename":"31-23.pdf","filesize":[{"value":"150.0 kB"}],"format":"application/pdf","license_note":"Copyright (c) 2013 by Fukuyama University","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"稗田雄三(発表論文抄録(2012))","url":"https://fukuyama-u.repo.nii.ac.jp/record/8761/files/31-23.pdf"},"version_id":"7a420e94-0a84-4193-b68f-1566569bcc95"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"total synthesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"(±)-carquinostatin A","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"(R)-(−)-carquinostatin A","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"(S)-(+)-carquinostatin A","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"lipase-QLM","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"asymmetric synthesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"(±)-Carquinostatin Aの全合成と(R)-(−)-及び (S)-(+)-Carquinostatin Aの不斉全合成研究(発表論文抄録(2012))","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"(±)-Carquinostatin Aの全合成と(R)-(−)-及び (S)-(+)-Carquinostatin Aの不斉全合成研究(発表論文抄録(2012))"},{"subitem_title":"Total Synthesis of (±)-Carquinostatin A, and Asymmetric Total Synthesis of (R)-(−)-Carquinostatin A and (S)-(+)-Carquinostatin A","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"18","path":["783"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-20"},"publish_date":"2017-12-20","publish_status":"0","recid":"8761","relation_version_is_last":true,"title":["(±)-Carquinostatin Aの全合成と(R)-(−)-及び (S)-(+)-Carquinostatin Aの不斉全合成研究(発表論文抄録(2012))"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-06-19T10:17:31.161849+00:00"}