{"created":"2023-06-19T09:50:36.162304+00:00","id":7515,"links":{},"metadata":{"_buckets":{"deposit":"781473b7-aa40-4998-ad7c-2524677d6ef7"},"_deposit":{"created_by":3,"id":"7515","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7515"},"status":"published"},"_oai":{"id":"oai:fukuyama-u.repo.nii.ac.jp:00007515","sets":["502:506:662:667"]},"author_link":["41182","41180","41185","41177","41187","41190","41178","41186","41188","41181","41179","41189","41183","41184"],"item_1_alternative_title_5":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_alternative_title":"The Interaction of Oxaliplatin(Pt(oxalate)(1R, 2R-cyclohexanediamine)) with DNA Visualized by an Atomic Force Microscope"}]},"item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-09","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"15","bibliographicPageStart":"11","bibliographicVolumeNumber":"5","bibliographic_titles":[{"bibliographic_title":"福山大学生命工学部研究年報"},{"bibliographic_title":"Annual report of Faculty of Life Science and Biotechnology, Fukuyama University","bibliographic_titleLang":"en"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The structural changes of DNA caused by PtCl_2(diaminocyclohexane (DACH)) were observed by an atomic force microscope (AFM). The AFM image of pUC19 DNA treated by Eco RI show that the DNA is shaped like a string. The AFM image of DNA treated with PtCl_2(DACH) at a ratio of platinum compound / base pair (r)=1.0 or 0.1 is very different from that of DNA and shows an ellipsoidal sphere in which the string of DNA was rolled up. The DNA treated with PtCl_2(DACH) at the ratio of platinum compound / base pair (r)=0.01 is also shaped into a ball, but the diameter of the ball is larger than that treated with PtCl_2(DACH) at the ratio of platinum compound / base pair (r)=1 or 0.1. It is known that, when the platinum complex binds to the double helix of DNA, a kink occurs in the DNA. The dramatic changes of the shape of the DNA from a string to a sphere were occurred by accumulating the DNA kink induced by the platinum complex.","subitem_description_type":"Other"}]},"item_1_full_name_7":{"attribute_name":"著者名よみ","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"41177","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヒロセ, ジュンゾ"}]},{"nameIdentifiers":[{"nameIdentifier":"41178","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヒカサ, ヒロユキ"}]},{"nameIdentifiers":[{"nameIdentifier":"41179","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ノジ, マサヒデ"}]},{"nameIdentifiers":[{"nameIdentifier":"41180","nameIdentifierScheme":"WEKO"}],"names":[{"name":"サト, タクシ"}]},{"nameIdentifiers":[{"nameIdentifier":"41181","nameIdentifierScheme":"WEKO"}],"names":[{"name":"サト, タカジ"}]},{"nameIdentifiers":[{"nameIdentifier":"41182","nameIdentifierScheme":"WEKO"}],"names":[{"name":"チクマ, マサヒコ"}]},{"nameIdentifiers":[{"nameIdentifier":"41183","nameIdentifierScheme":"WEKO"}],"names":[{"name":"キダニ, ヨシノリ"}]}]},"item_1_full_name_8":{"attribute_name":"著者名(英)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"41184","nameIdentifierScheme":"WEKO"}],"names":[{"name":"HIROSE, Junzo","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"41185","nameIdentifierScheme":"WEKO"}],"names":[{"name":"HIKASA, Hiroyuki","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"41186","nameIdentifierScheme":"WEKO"}],"names":[{"name":"NOJI, Masahide","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"41187","nameIdentifierScheme":"WEKO"}],"names":[{"name":"SATO, Takushi","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"41188","nameIdentifierScheme":"WEKO"}],"names":[{"name":"SATO, Takaji","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"41189","nameIdentifierScheme":"WEKO"}],"names":[{"name":"CHIKUMA, Masahiko","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"41190","nameIdentifierScheme":"WEKO"}],"names":[{"name":"KIDANI, Yoshinori","nameLang":"en"}]}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11870542","subitem_source_identifier_type":"NCID"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Applied Biological Sciences, Faculty of Life Science and Biotechnology., Fukuyama University"},{"subitem_text_language":"en","subitem_text_value":"Department of Applied Biological Sciences, Faculty of Life Science and Biotechnology., Fukuyama University"},{"subitem_text_language":"en","subitem_text_value":"Graduate School of Health Science, Suzuka University of Medical Science"},{"subitem_text_language":"en","subitem_text_value":"Osaka University of Pharmaceutical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Osaka University of Pharmaceutical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Osaka University of Pharmaceutical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Faculty of Pharmaceutical Sciences, Nagoya City University"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"福山大学"},{"subitem_text_value":"福山大学"},{"subitem_text_value":"/"},{"subitem_text_value":"/ /"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2006-09-01"}],"displaytype":"detail","filename":"KJ00005782202.pdf","filesize":[{"value":"983.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"url":"https://fukuyama-u.repo.nii.ac.jp/record/7515/files/KJ00005782202.pdf"},"version_id":"c57caf6a-aec2-40c3-9997-30cd040d5805"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"anticancer platinum complex","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"AFM image","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DNA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"oxaliplatin","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The Interaction of Oxaliplatin(Pt(oxalate)(1R, 2R-cyclohexanediamine)) with DNA Visualized by an Atomic Force Microscope","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Interaction of Oxaliplatin(Pt(oxalate)(1R, 2R-cyclohexanediamine)) with DNA Visualized by an Atomic Force Microscope","subitem_title_language":"en"}]},"item_type_id":"1","owner":"3","path":["667"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-09-01"},"publish_date":"2006-09-01","publish_status":"0","recid":"7515","relation_version_is_last":true,"title":["The Interaction of Oxaliplatin(Pt(oxalate)(1R, 2R-cyclohexanediamine)) with DNA Visualized by an Atomic Force Microscope"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T10:41:42.054436+00:00"}