@article{oai:fukuyama-u.repo.nii.ac.jp:00007179,
 author = {田淵, 紀彦},
 journal = {福山大学薬学部研究年報, Annual report of the Faculty of Pharmacy & Pharmaceutical Sciences, Fukuyama University},
 month = {},
 note = {P(論文), Lysosomal membrane glycoprotein termed LGP85 or LIMP II has a COOH terminal cytoplasmic tail whose amino acid sequence is R_<459>GQGSMDEGTADERAPLIRT_<478>. The sequence of D_<470>EXXXLI_<476> is crucial for its binding adaptor protein complexes, AP-1 and AP-3, which are involved in vesicular transport to endosomal and lysosomal system. Early and late endosomes and lysosomes constitute this system. I have studied how the sequence determines the localization of LGP85 in the endosomal and lysosomal system. D_<470> and E_<471> function to transport of LGP85 from early endosomes to late endosomes. I_<476> of LI motif is a determinant for proper distribution of LGP85 between late endosomes and lysosomes. In this review, I describe an independent role of pivotal amino acids of the signal sequence in localization of LGP85 in the endocytic organelles.},
 pages = {29--52},
 title = {リソソーム膜糖蛋白質LGP85/LIMP IIのリソソーム局在化シグナルの解析},
 volume = {19},
 year = {2001}
}