{"_buckets": {"deposit": "da95b54f-e75b-41e6-ac55-b3cf2ed30f80"}, "_deposit": {"created_by": 3, "id": "7080", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "7080"}, "status": "published"}, "_oai": {"id": "oai:fukuyama-u.repo.nii.ac.jp:00007080", "sets": ["643"]}, "author_link": ["36738", "36741", "36740", "36742", "36747", "36746", "36749", "36748", "36752", "36750", "36743", "36751", "36739", "36744", "36745"], "item_1_biblio_info_14": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1998", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "65", "bibliographicVolumeNumber": "16", "bibliographic_titles": [{"bibliographic_title": "福山大学薬学部研究年報"}, {"bibliographic_title": "Annual report of the Faculty of Pharmacy \u0026 Pharmaceutical Sciences, Fukuyama University", "bibliographic_titleLang": "en"}]}]}, "item_1_creator_6": {"attribute_name": "著者名(日)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "植木, 寛"}], "nameIdentifiers": [{"nameIdentifier": "36738", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "三樹, 修一"}], "nameIdentifiers": [{"nameIdentifier": "36739", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "川嶋, 善仁"}], "nameIdentifiers": [{"nameIdentifier": "36740", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "本屋敷, 敏雄"}], "nameIdentifiers": [{"nameIdentifier": "36741", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "森田, 哲生"}], "nameIdentifiers": [{"nameIdentifier": "36742", "nameIdentifierScheme": "WEKO"}]}]}, "item_1_description_1": {"attribute_name": "ページ属性", "attribute_value_mlt": [{"subitem_description": "P(論文)", "subitem_description_type": "Other"}]}, "item_1_description_11": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "バナデートは、摘出ラット脂肪組織の穎粒画分に存在するチロシンキナーゼ(PTK)、ミエリン塩基性蛋白質キナーゼ(MBPK)、cAMPホスホジエステラーゼ(PDE)の活性を促進した。部分精製PDE活性はPTKやMBPK画分の添加によって増強した。MBPK画分はウエスタンプロット解析によってMAPキナーゼ(MAPK)を含むことが確認された。これからの結果は、バナデートがバナデート感受性PTKによるMBPK、恐らくMAPK、の活性化を介してPDEの活性を増強することを示唆する。", "subitem_description_type": "Other"}]}, "item_1_description_12": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "Vanadate stimulated all activities of protein tyrosine kinase(PTK), myelin basic protein kinase(MBPK), and cAMP phosphodiesterase(PDE) in the particulate of rat fat pads. The partially purified PDE activity was stimulated by the addition of PTK and MBPK fractions. A fraction of MBPK was identified to contain mitogen-activated protein kinases(MAPKs) by Western blot analysis. These results suggest that vanadate stimulates in part the PDE activity through the activation of MBPK, probably MAPKs, by PTK sensitive to vanadate.", "subitem_description_type": "Other"}]}, "item_1_full_name_7": {"attribute_name": "著者名よみ", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "36743", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "ウエキ, ヒロシ"}]}, {"nameIdentifiers": [{"nameIdentifier": "36744", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "ミツギ, シュウイチ"}]}, {"nameIdentifiers": [{"nameIdentifier": "36745", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "カワシマ, ヨシヒト"}]}, {"nameIdentifiers": [{"nameIdentifier": "36746", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "モトヤシキ, トシオ"}]}, {"nameIdentifiers": [{"nameIdentifier": "36747", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "モリタ, テツオ"}]}]}, "item_1_full_name_8": {"attribute_name": "著者名(英)", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "36748", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ueki, Hiroshi", "nameLang": "en"}]}, {"nameIdentifiers": [{"nameIdentifier": "36749", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Mitsugi, Shuichi", "nameLang": "en"}]}, {"nameIdentifiers": [{"nameIdentifier": "36750", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kawashima, Yoshihito", "nameLang": "en"}]}, {"nameIdentifiers": [{"nameIdentifier": "36751", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Motoyashiki, Toshio", "nameLang": "en"}]}, {"nameIdentifiers": [{"nameIdentifier": "36752", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Morita, Tetsuo", "nameLang": "en"}]}]}, "item_1_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN10064550", "subitem_source_identifier_type": "NCID"}]}, "item_1_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "FACULTY OF PHARMACY \u0026 PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY"}, {"subitem_text_language": "en", "subitem_text_value": "FACULTY OF PHARMACY \u0026 PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY"}, {"subitem_text_language": "en", "subitem_text_value": "FACULTY OF PHARMACY \u0026 PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY"}, {"subitem_text_language": "en", "subitem_text_value": "FACULTY OF PHARMACY \u0026 PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY"}, {"subitem_text_language": "en", "subitem_text_value": "FACULTY OF PHARMACY \u0026 PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY"}]}, "item_1_text_2": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_text_value": "発表論文抄録"}]}, "item_1_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "福山大学薬学部"}, {"subitem_text_value": "福山大学薬学部"}, {"subitem_text_value": "福山大学薬学部"}, {"subitem_text_value": "福山大学薬学部"}, {"subitem_text_value": "福山大学薬学部"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "1998-01-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00005784677.pdf", "filesize": [{"value": "49.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 49900.0, "url": {"url": "https://fukuyama-u.repo.nii.ac.jp/record/7080/files/KJ00005784677.pdf"}, "version_id": "cd68f836-1ba0-4201-8dae-9cd14479e889"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "バナデートはチロシンキナーゼによるミエリン塩基性蛋白質キナーゼの活性化を介して摘出ラット脂肪組織のcGMP阻害性cAMPホスホジエステラーゼ活性を促進する", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "バナデートはチロシンキナーゼによるミエリン塩基性蛋白質キナーゼの活性化を介して摘出ラット脂肪組織のcGMP阻害性cAMPホスホジエステラーゼ活性を促進する"}, {"subitem_title": "Orthovanadate stimulates cyclic guanosine monophosphate-inhibited cyclic adenosine monophosphate phosphodiesterase activity in isolated rat fat pads through activation of particulate myelin basic protein kinase by protein tyrosine kinase", "subitem_title_language": "en"}]}, "item_type_id": "1", "owner": "3", "path": ["643"], "permalink_uri": "https://fukuyama-u.repo.nii.ac.jp/records/7080", "pubdate": {"attribute_name": "公開日", "attribute_value": "1998-01-01"}, "publish_date": "1998-01-01", "publish_status": "0", "recid": "7080", "relation": {}, "relation_version_is_last": true, "title": ["バナデートはチロシンキナーゼによるミエリン塩基性蛋白質キナーゼの活性化を介して摘出ラット脂肪組織のcGMP阻害性cAMPホスホジエステラーゼ活性を促進する"], "weko_shared_id": -1}