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インドネシア薬用植物第XXI報 : Erythrina variegata樹皮とMaclura cochinchinensis根から単離したNa+/H+交換阻害物質
https://fukuyama-u.repo.nii.ac.jp/records/7079
https://fukuyama-u.repo.nii.ac.jp/records/70792708c5b6-d96b-4f12-9e3a-2d65aad06c1d
名前 / ファイル | ライセンス | アクション |
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KJ00005784676.pdf (57.9 kB)
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
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公開日 | 1998-01-01 | |||||
タイトル | ||||||
タイトル | インドネシア薬用植物第XXI報 : Erythrina variegata樹皮とMaclura cochinchinensis根から単離したNa+/H+交換阻害物質 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Indonesian Medicinal Plants. XXI. Inhibitors of Na^+/H^+ Exchanger from the Bark of Erythrina variegata and the Roots of Maclura cochinchinensis | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ページ属性 | ||||||
内容記述タイプ | Other | |||||
内容記述 | P(論文) | |||||
記事種別(日) | ||||||
値 | 発表論文抄録 | |||||
著者名(日) |
小林, 資正
× 小林, 資正× マハムド, タイフォー× 吉岡, 直樹× 澁谷, 博孝× 北川, 勲 |
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著者名よみ | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36729 | |||||
姓名 | コバヤシ, モトマサ | |||||
著者名よみ | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36730 | |||||
姓名 | / ヨシオカ, ナオキ | |||||
著者名よみ | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36731 | |||||
姓名 | シブヤ, ヒロタカ | |||||
著者名よみ | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36732 | |||||
姓名 | キタガワ, イサオ | |||||
著者名(英) | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36733 | |||||
姓名 | Kobayashi, Motomasa | |||||
言語 | en | |||||
著者名(英) | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36734 | |||||
姓名 | Mahmud, Taifo | |||||
言語 | en | |||||
著者名(英) | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36735 | |||||
姓名 | Yoshioka, Naoki | |||||
言語 | en | |||||
著者名(英) | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36736 | |||||
姓名 | Shibuya, Hirotaka | |||||
言語 | en | |||||
著者名(英) | ||||||
識別子Scheme | WEKO | |||||
識別子 | 36737 | |||||
姓名 | Kitagawa, Isao | |||||
言語 | en | |||||
著者所属(日) | ||||||
値 | 大阪大学薬学部 | |||||
著者所属(日) | ||||||
値 | 大阪大学薬学部 | |||||
著者所属(日) | ||||||
値 | 大阪大学薬学部 | |||||
著者所属(日) | ||||||
値 | 福山大学薬学部 | |||||
著者所属(日) | ||||||
値 | 大阪大学薬学部 | |||||
著者所属(英) | ||||||
言語 | en | |||||
値 | Faculty of Pharmaceutical Sciences, Osaka University | |||||
著者所属(英) | ||||||
言語 | en | |||||
値 | Faculty of Pharmaceutical Sciences, Osaka University | |||||
著者所属(英) | ||||||
言語 | en | |||||
値 | Faculty of Pharmaceutical Sciences, Osaka University | |||||
著者所属(英) | ||||||
言語 | en | |||||
値 | FACULTY OF PHARMACY & PHARMACEUTICAL SCIENCES FUKUYAMA UNIVERSITY | |||||
著者所属(英) | ||||||
言語 | en | |||||
値 | Faculty of Pharmaceutical Sciences, Osaka University | |||||
抄録(日) | ||||||
内容記述タイプ | Other | |||||
内容記述 | インドネシアの薬用植物であるErythrina variegata樹皮およびMacluracochinchinensis根からerythrinin B,euchrenone b_<10>,及び1,3,5-trihydroxy-4-(3-methylbut-2-enyl)xanthen-9-oneを単離し、それぞれに1.25,1.25,10μg/mlの濃度でNa^+/H^+交換阻害活性があることを明らかにした。さらに、M.cochinchinensis根から3種の新規プレニルキサントン、isocudraniaxanthones B,A及びisoalvaxanthoneを単離し、それらの化学構造を化学的及び物理化学的手法を用いて明らかにした。 | |||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Through bioassay-guided separation of the methanol extracts of Indonesian medicinal plants, three inhibitors of the Na^+/H^+ exchange system, erythrinin B, euchrenone b10, and 1,3,5-trihydroxy-4-(3-methylbut-2-enyl) xanthen-9-one, were isolated from the bark of Erythrina variegata (Fabaceae) and the roots of Maclura cochinchinensis (Moraceae). These compounds significantly inhibited the Na^+/H^+ exchange system of arterial smooth muscle cells, with minimum inhibitory concentrations of 1.25, 1.25, and 10 μg/ml, respectively. Three new prenylated xanthones named isocudraniaxanthones B and A and isoalvaxanthone were also isolated from M. cochinchinensis and the chemical structures were elucidated on the bases of their chemical and physicochemical properties. | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10064550 | |||||
書誌情報 |
福山大学薬学部研究年報 en : Annual report of the Faculty of Pharmacy & Pharmaceutical Sciences, Fukuyama University 巻 16, p. 63-64, 発行日 1998 |